Passer au contenu

plasma product

plasma product

juillet 21, 2022

Plasma protein therapies are unique treatments that are used to replace missing or lacking proteins found in plasma. For people who require plasma protein therapies, these treatments are essential and life-sustaining, enabling patients to live healthy, well-rounded lives.

If you’d like to learn more about what exactly plasma is and the life-altering therapies it is used to create, keep reading to find out. 

What Is Blood Plasma?

Before we delve more into what plasma protein therapies are, it’s important to first understand what plasma is. Plasma is a straw-coloured liquid portion of blood. It is the largest component of blood, and it contains essential proteins that are needed for blood clotting and immunity. 

How Are Plasma Protein Therapies Created? 

Plasma goes through an extensive manufacturing process that ranges from 7 – 12 months after it has been donated. Plasma fractionation is part of this manufacturing process, and it entails using purification techniques, like precipitation, centrifugation, separation, and filtration, to transform plasma into various therapies. 

After plasma has been manufactured into plasma protein therapies, it can then be administered to immunocompromised patients who require these treatments on a consistent basis.

Plasma that is frozen can be used in hospitals and other clinical settings for up to 12 months after donation. Because of plasma’s blood clotting abilities, it can be used to treat victims of major accidents in emergency cases. However, most donated plasma is used to make pharmaceutical products. 

What Types of Plasma Protein Therapies Are There?

There are four main types of plasma protein therapies:

  • Albumin
  • IVIG (Intravenous Immuoglobulin)
  • Alpha-1 Antitrypsin 
  • Coagulation Factors

Each of these therapies are used to treat different rare and chronic conditions. 

Who Needs Plasma Protein Therapies? 

Millions of people worldwide require plasma protein therapies for a variety of reasons. People with immune deficiencies, autoimmune disorders, bleeding disorders, and more rely on plasma protein therapies in order to live healthy lives. 

Now that you know what plasma protein therapies are, we hope you’ll consider making a donation in the near future. Patients are only able receive the life-sustaining treatments they need due to the generosity of plasma donors, and every donation helps! Book a plasma donation appointment at a Canadian Plasma Resources centre near you to help us help others. 

plasma product

février 28, 2022

Plasma is the most abundant component of our blood. It contains specialized proteins that help fight off infections and can be used to create life-saving medicines. These medicines, which are also commonly referred to as plasma protein therapies, treat a host of rare and chronic diseases. 

If you’d like to learn more about the conditions plasma is used to treat, keep reading to find out. 

What Is Plasma Made Of?

Plasma is a straw-coloured mixture made of water, salts, and proteins. The proteins contained in it include:

  • Immunoglobulins
  • Alpha-1 proteinase inhibitor 
  • Clotting factors
  • C1 esterase inhibitor

Each of these proteins can be used to create therapies that treat specific diseases. 

What Does Plasma Donation Do?

Plasma donation is the process by which the plasma that is used to create life-saving therapies is collected. To collect plasma, donors undergo a process called plasmapheresis, which removes blood from the body, separates out plasma, and returns all other blood components to the body. This type of plasma donation is known as source plasma donation, and it brings in three times more plasma than just removing plasma from a blood donation. 

After plasma is collected, it undergoes an extensive manufacturing process that can take anywhere from seven to 12 months to complete. Once plasma has been manufactured into medicinal products, it is then administered to immunocompromised patients. 

Who Needs Plasma Therapies?

Plasma protein therapies are used to treat a number of bleeding disorders, autoimmune diseases, and immunodeficiencies. Here are some specific conditions that plasma is used to treat: 

1. Primary Immunodeficiency Diseases (PIDDs)

PIDDs are a group of more than 300 diseases that are caused by missing immunoglobulins, also known as antibodies. Antibodies are produced by your immune system in response to foreign invaders and can help prevent illness. 

Patients who have a PIDD often have persistent, recurrent infections and are chronically ill as a result. PIDDs can be treated with immunoglobulin replacement therapies. 

2. Alpha-1 Antitrypsin Deficiency

This rare genetic disorder is caused by a lack of the protein alpha-1 proteinase inhibitor. Alpha-1 proteinase inhibitor protects your lung tissue from being damaged. 

Patients living with alpha-1 antitrypsin deficiency may have chronic emphysema and/or liver damage. Alpha-1 proteinase inhibitor therapies can help manage this condition. 

3. Hemophilia

Hemophilia is a bleeding disorder that is caused by missing or mutated clotting factor proteins. It causes recurrent bleeding episodes in the skin, muscles, and/or joints, the latter of which can ultimately lead to crippling joint disease. This disorder can be treated via hormone replacement therapies that are made from clotting factors. 

4. Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

CIDP is a form of chronic autoimmune neuropathy that causes your immune system to attack your nerve coating. This, in turn, impairs the ability of your brain to deliver messages to your body. 

Impaired motor function, progressive weakness, and loss of limb function are some of the symptoms patients who have CIDP may experience. Intravenous immunoglobulin therapies can be used to treat this condition. 

5. Hereditary Angioedema 

Caused by missing or low levels of the C1 esterase inhibitor protein, hereditary angioedema is an inherited disorder that is characterized by persistent and severe swelling. This swelling can be fatal if your airway is obstructed. Plasma-derived products made from the C1-inhibitor protein are effective treatments for hereditary angioedema. 

The fact that plasma can be used to treat so many rare diseases is one of the reasons why plasma donation is so important. By donating plasma, you can help improve the lives of patients living with these conditions. Book your next plasma donation appointment today to change someone else’s life for the better. 

plasma product

janvier 31, 2022

Plasma, a protein-rich part of blood, is an essential component of several life-saving therapies. The patients who receive plasma-derived medicinal products often need them for the rest of their lives. One example of these essential treatments is intravenous immunoglobulin (IVIg). 

If you haven’t heard of IVIg before, keep reading to find out what it is and how plasma is used to create this incredible therapy! 

What Is IVIg Infusion Treatment For?

IVIg is a treatment that is made from immunoglobulins, which are antibodies naturally produced by the body’s immune system. Immunoglobulins help fight infection and disease, and they can treat various medical conditions when they are made into IVIg treatments. IVIg treatments are administered intravenously, hence the name intravenous immunoglobulin. 

Who Needs to Receive IVIg Treatments?

There are two main reasons why someone might need to receive IVIg treatments, the first being that your body does not make enough antibodies. IVIg therapies can provide extra antibodies that your body is unable to make on its own and, in turn, help your body fight off infections. These antibodies typically last for several weeks to months. 

The most common types of primary immune deficiencies are caused by antibody deficiencies and can be treated with IVIg therapies. Because the antibodies provided by IVIg don’t last forever, regular treatments are needed. 

Another reason why you may need to receive IVIg treatments is if your immune system starts producing antibodies that destroy your own cells. This phenomenon occurs in the following conditions:

  • Chronic inflammatory demyelinating polyneuropathy (CIDP)
  • Immune thrombocytopenic purpura (ITP)
  • Guillain-Barré syndrome (GBS)

IVIg is believed to help prevent your immune system from attacking your own body if you are living with one of these conditions. 

How Is Plasma Used to Create IVIg Treatments?

Plasma contains important antibodies that protect the body against foreign invaders. Without plasma donations being made by thousands of different people, creating IVIg treatments would not be possible. 

IVIg is prepared from the pooled plasma of healthy donors. An extensive manufacturing process is involved in the creation of IVIg therapies. Plasma fractionation, filtration, and viral reduction procedures are just some of the steps involved in creating IVIg therapies that are safe to use. 

Evidently, IVIg is life-changing therapy that has made it possible for people who have rare and chronic conditions to live healthier lives. To help create IVIg therapies and change someone else’s life for the better, book a plasma donation appointment today. Every donation matters!